Global Innovation Index 2015

ТОП-50 фармкомпаний мира по итогам 2015 года

Не смотря на то, что список первых 50 компаний существенно не меняется из года в год, их позиции внутри списка постоянно меняется. Безусловно, такие сдвиги происходят за счет новых лончей, инновационных промо- кампаний, эффективных маркетинговых и коммерческих активностей, грамотным стратегиям роста. Так, именно благодаря этому, Pfizer заняла первое место в текущем рейтинге, обогнав Novartis.

В первой десятке продолжает неплохо себя чувствовать прошлогодний новичок – Gilead Sciences. Американский биотехнологический гигант завоевал себе место под солнцем за счет своего инновационного продукта для применения при лечении гепатита С. Однако, если Gilead не расширит свой портфолио другими продуктами, столь эффективными, как тот же Harvoni®, например, то ее достаточно быстро сместят из первой десятки другие игроки.

В рейтинге компании представлены еще без объединения Teva и Allergan, Shire и Baxalta. Обе объединенные компании в следующем рейтинге существенно поднимутся вверх. Объединенная Teva – в первую десятку, а Shire – во вторую, став, таким образом, еще и самым крупным игроком в мире в нише орфанных препаратов.

Примечание: обзор составлен изданием Pharmaceutical Executive на основе данных компании Evaluate по состоянию на апрель 2016 года.

Прошлогодний рейтинг лежит здесь: ссылка

Eugene Brovko

Partner at UPharma Consulting, Business-Consulting

2015's Biggest Medtech Companies

Stryker's GetAroundKnee boasts a single-radius design, enabling the knee to have the same radius when flexed.

10. Stryker

$9.0 billion in revenue in the fiscal year ended Dec. 31, 2013

Stryker for the first half of 2014 saw its sales rise nearly 7% year over year, to nearly $4.7 billion. But its earnings have been taking a beating, down three-fifths to $198 million. Profits have been especially hurt because of settlements related to Rejuvinate all-metal hip implant lawsuits. Stryker has been setting aside funds to cover $790 million to $1.2 billion in losses related to the lawsuits, according to its most recent annual report.

The Kalamazoo, MI–based ortho devices maker announced earlier this year that it is rounding out its portfolio through the acquisition of Small Bone Innovations Inc. (Sbi), a privately held company headquartered in Morrisville, PA, at a net cost of $285 million. The deal included SBi's Scandinavian Total Ankle Replacement System, referred to as the STAR Ankle. Sbi touted their STAR Ankle, sold globally in over 40 countries, as the only PMA approved,cementless, three-piece total ankle replacement system.

Novartis reportedly would like to have a prototype using Google “smart lens” technology ready for research and development reviews by early next year.

9. Novartis AG

$10.5 billion in revenue in its Alcon division (eye care products) in the fiscal year ended Dec. 31, 2013

Swiss pharmaceutical giant Novartis’ vision care products division Alcon makes up 18% of its revenue. Alconrevenue was up 3% in 2013.

When the news came out in January that Google planned to develop a contact lens that could help diabetics keep track of their blood glucose levels, company officials said they were looking for partners with expertise in bringing such products to market.

That seems to be exactly what Google has found in the Novartis' Alcon, which has agreed to in-license Google’s “smart lens” technology for all ocular medical uses.

Cardinal Health in June announced the 2 millionth shipment of the Mynx VascularClosureDevice (VCD).

8. Cardinal Health

$11.0 billion in revenue in its medical device segment in the fiscal year ended June 30, 2014

One of the more exciting pieces of medical device news for Dublin, OH–based Cardinal Health came in April, when it announced it would spend $320 million to acquire AccessClosure and its extravascular closure devices technology. AccessClosure’s Mynx family of patient-friendly vascular closure devices helps physicians seal the femoral artery using a unique, secure sealant. The sealant dissolves within 30 days, leaving nothing behind but a healed artery. The idea is to allow patients to safely ambulate more quickly—enabling them to get home faster.

The company’s Medical Segment saw revenue grow 9%, to nearly $11 billion, for the fiscal year ended June 30, even as overall revenue declined 10%, to $91 billion. (Much of Cardinal Health’s revenue comes from pharmaceuticals.)

Becton, Dickinson and Co. in August announced the retail pharmacy launch of the BDAutoShield Duo, which it boasts as the only pen needle with patented dual front and back-end shields to provide greater convenience and safety before and after injecting.

7. BD

$11.9 billion in combined annual revenue following merger with CareFusion

Becton, Dickinson and Co. (BD)
$8.1 billion in revenue in the fiscal year ended Sept. 30, 2013

CareFusion
$3.8 billion in sales in the fiscal year ended June 30, 2014

Franklin Lakes, NJ–based Becton, Dickinson (BD) announced in early October that it will spend $12 billion to acquire San Diego–based CareFusion in a deal expected to close in the first half of 2015. The two companies combined have experienced annual revenue of $11.9, so the merger should create one of the 10 largest medical device companies in the world. This is certainly a pretty strategic acquisition where each company brings something to the table.

Medtech giant BD has a more bread-and-butter lineup of medical supplies, devices, lab equipment and diagnostic products. Its product lineup includes disposable needles, syringes and intravenous catheters. CareFusion’s flagship product lines are more high tech and include patient identification systems, the Pyxis automated dispensing device, the Alaris IV device, ventilators, skin prep products, infection surveillance systems and surgical instruments.

BD plans for CareFusion to operate as part of its medical business.

CareFusion comes with some baggage though. The company has seen 10 serious recalls since the start of 2012. And early this year, it agreed to pay the federal government $40.1 million to settle allegations that it violated the False Claims Act by paying kickbacks and promoting its products for uses that were not FDA-approved.

Philips Healthcare is investigating the use of Google Glass as a way to augment the information that its patient monitoring systems provide. The system is still experimental.

6. Koninklijke Philips Electronics

$12.1 billion (9.6 billion Euros) in revenue in its  Philips Healthcare division in the fiscal year ended Dec. 31 2013. (Note: Philips has plans to make this business unit independent.)

The Dutch multinational industrial giant has been grappling with a challenging economic environment in Western Europe and the United States. Early in the summer, Philips announced that its top health care executive DeborahDiSanzo had left the company amid disappointing earnings results. Then in September, Philips announced it would separate its healthcare and lighting businesses, with the possibility of spinning off the new lighting company with an IPO by 2016. There was more rough news for Philips Healthcare in early October: a U.S. federal jury's decision to award Irvine, CA–based Masimo Corp. $467 million in a patent infringement case against the Dutch multinational. Philips plans to appeal the decision.

In 2013, Fresenius announced that it had produced 1 billion dialyzers since the company was founded. Shown here is a cross-section of a dialyzer from the company, which are used to filter out toxins from the blood in dialysis.

5. Fresenius Medical Care AG & Co. KGAA

$14.6 billion in revenue in the fiscal year ended Dec. 31, 2013

The biggest provider of kidney dialysis products and services, Fresenius Medical Care has been named to Forbes’ World’s Most Innovative companies in 2011, 2012, and 2013. Last year, the company ranked as the sixth largest medical device firm.

Siemens Healthcare in May announced FDA clearance for the Artis One—an angiography system boasting low space requirements. It is designed for routine interventions, including revascularizations of peripheral vessel occlusions, functional tests of dialysis shunts in patients with kidney failure, diagnostic or minimally invasive angiographic treatment of narrowed coronary arteries, and pacemaker implantations. Siemens announced in late September that St. Johns Hospital and Medical Center in Detroit has become the first U.S. healthcare facility to install the Artis.

4. Siemens AG

$17.3 billion in sales (13.6 billion Euros) in its healthcare sector in the fiscal year ended Sept. 30, 2013

As in the case of GE and Philips, Siemens is another huge conglomerate seeking focus on its healthcare business amid flat sales. As part of the strategy, the German multinational earlier this year announced it was selling its healthcare IT business to Cerner Corp. for $1.3 billion.

Along with headwinds from the strength of the Euro, Siemens has blamed weak economic conditions in Europe, uncertainty in the healthcare market, the excise tax on medical devices in the U.S., and—as with other multinationals—slowing growth in China.

(Note: Siemens' health IT business has about $1.2 billion in annual revenue, according to Reuters.)

GE’s Vscan pocket-sized ultrasound system GE has won a slew of awards.

3. General Electric Co.

$18.2 billion in revenue in its healthcare segment in the fiscal year ended Dec. 31, 2013

The conglomerate has a diversified range of products, making everything from CT scanners to jet engines. The company recently announced that it is selling its famed appliance division amidst sluggish sales. Healthcare is another sector where the company is experiencing soft results.

The company’s CEO Jeffrey Immelt, however, is committed to its healthcare. Just on Monday, October 6, the company announced that GE Healthcare CEO John Dineen was leaving, to be replaced by John Flannery, who had been GE’s senior vice president of business development.

The Micra pacemaker, billed by Medtronic as the world’s smallest, is an order of magnitude smaller than current generation pacemakers. Medtronic developed the device in house, as we detailed in the article “How Medtronic Made the World's Smallest Pacemaker.”

2. Medtronic plc

Assuming the merger goes through as planned, Medtronic and Covidien would have roughly $27.2 billion a year in sales between them.

Medtronic
$17 billion in revenue in the fiscal year ended April 25, 2014

Covidien
$10.2 billion in revenue in the fiscal year ended Sept. 27, 2013

By acquiring Covidien for $43 billion, Medtronic could give J&J a run for its money as the company with the largest device and diagnostics business. In 2013, J&J had nearly $28.1 billion in sales—roughly $10 billion more than its nearest competitor, Siemens. But Medtronic plc would be $27 billion-a-year company in itself. On top of that, both Medtronic and Covidien already had an aggressive plan to expand their presence in emerging markets. In 2015, it’s anybody’s guess which medical device company will bring in the most revenue.

The ThermoCool Smart Touch catheter from J&J’s Biosense Webster division became the first catheter ablation device with direct-contact force technology to win FDA approval. The device offers real-time measurement of contact force during catheter ablation, enabling it to monitor atrial fibrillation.

1. Johnson & Johnson

$28.1 billion in sales in J&J’s Medical Devices and Diagnostics segment in the fiscal year ended Dec. 30, 2013

Johnson & Johnson stakes claim to “the world’s largest medical devices and diagnostics business,” and it is aggressively defending that title. The company says it will unveil more than 30 major products by the end of 2016. J&J is also aggressively expanding into emerging markets and has a nearly $2 billion annual R&D budget.

Top 10 Pharma companies by sales, profits, assets & market value

Top 10 pharmaceutical companies of 2015

Best Global Brands 2015

Valentina Pasquali

The American Marketing Association defines a “brand” as “a name, term, design, symbol or any other feature that identifies one seller's good or service as distinct from those of other sellers.” Some marketing researchers assert that brands are one of the most valuable assets that a company has.

According to Millward Brown Optimor, “strong brands have the power to create business value. They impact much more than revenues and profit margins. Strong brands create competitive advantages by commanding a price premium and decrease the cost of entry into new markets and categories. They reduce business risk and help attract and retain talented staff.”

“Brand equity” is defined by the American Marketing Association as “the value of a brand” (although not in the financial sense of “value”), while, according to P. Kotler and K. Keller in their book Marketing Management, it is “the added value endowed to products and services.” Keller, in Strategic Brand Management, writes that a brand “has positive customer-based brand equity when consumers react more favorably to a product and the way it is marketed when the brand is identified than when it is not.” David Aaker (Managing Brand Equity) calls it “the set of assets and liabilities linked to a brand’s name and symbol that adds to or subtracts from the value provided by a product or service to a firm and/or that firm’s customers.”

The various definitions are important to define the concept but do not lead to a single measure of brand equity.

“Brand value” is often confused with brand equity, but the former refers more specifically to the financial value of a brand. Therefore, Kotler and Keller define “brand valuation” as “an estimate of the total financial value of the brand.”

There is no standardized or accepted definition of brand value or brand valuation. Nevertheless, Interbrand and Millward Brown Optimor (MBO) have developed rankings that are well respected. Interbrand characterizes its method as “proven, straightforward and profound. It examines brands through the lens of financial strength, the importance of the brand in driving consumer selection, and the likelihood of ongoing revenue generated by the brand.” Millward Brown Optimor calls its BrandZ “the most reliable, comprehensive and useful brand valuation ranking available,” a database that provides a “detailed, quantified, understanding of consumer decision-making worldwide.”

MBO | InterBrand

MillwardBrown Optimor 2015 BrandZ Top 100

Rank	Brand	Category	Brand Value ($M)
1	Apple	Technology	246,992
2	Google	Technology	173,652
3	Microsoft	Technology	115,500
4	IBM	Technology	93,987
5	Visa	Payments	91,962
6	AT&T	Telecom Providers	89,492
7	Verizon	Telecom Providers	86,009
8	Coca-Cola	Soft Drinks	83,841
9	McDonald's	Fast Food	81,162
10	Marlboro	Tobacco	80,352
11	Tencent	Technology	76,572
12	Facebook	Technology	71,121
13	Alibaba Group	Retail	66,375
14	Amazon.com	Retail	62,292
15	China Mobile	Telecom Providers	59,895
16	Wells Fargo	Regional Banks	59,310
17	General Electric	Conglomerate	59,272
18	UPS	Logistics	51,798
19	Disney	Entertainment	42,962
20	Mastercard	Payments	40,188
21	Baidu	Technology	40,041
22	ICBC	Regional Banks	38,808
23	Vodofone	Telecom Providers	38,461
24	SAP	Technology	38,225
25	American Express	Payments	38,093
26	Walmart	Retail	35,245
27	T-mobile	Telecom Providers	33,834
28	Nike	Apparel	29,717
29	Starbucks	Fast Food	29,313
30	Toyota	Cars	28,913
31	The Home Depot	Retail	27,705
32	Louis Vuitton	Luxury	27,445
33	Budweiser	Beer	26,657
34	BMW	Cars	26,349
35	HSBC	Global Banks	24,029
36	RBC	Regional Banks	23,989
37	Pampers	Baby Care	23,757
38	L'Oréal Paris	Personal Care	23,376
39	HP	Technology	23,039
40	Subway	Fast Food	22,561
41	China Construction Bank	Regional Banks	22,065
42	Zara	Apparel	22,036
43	Mercedes-Benz	Cars	21,786
44	Oracle	Technology	21,680
45	Samsung	Technology	21,602
46	Movistar	Telecom Providers	21,215
47	TD Bank	Regional Banks	20,638
48	Commonwealth Bank	Regional Banks	20,599
49	ExxonMobil	Oil & Gas	20,412
50	Agricultural Bank of China	Regional Banks	20,189
51	Accenture	Technology	20,183
52	Gillette	Personal Care	19,737
53	FedEx	Logistics	19,566
54	Shell	Oil & Gas	18,943
55	Hermes Paris	Luxury	18,938
56	Intel	Technology	18,385
57	Colgate	Personal Care	17,977
58	BT	Telecom Providers	17,953
59	ANZ Bank	Regional Banks	17,702
60	Citi	Global Banks	17,486
61	Orange	Telecom Providers	17,384
62	China Life	Insurance	17,365
63	Sinopec	Oil & Gas	17,267
64	Ikea	Retail	17,025
65	Bank of China	Regional Banks	16,438
66	DHL	Logistics	16,301
67	CISCO	Technology	16,060
68	Pingan	Insurance	15,959
69	SIEMENS	Technology	15,796
70	Huawei	Technology	15,335
71	PetroChina	Oil & Gas	15,022
72	US BANK	Regional Banks	14,786
73	eBay	Retail	14,171
74	HDFC Bank	Regional Banks	14,027
75	H&M	Apparel	13,827
76	Gucci	Luxury	13,800
77	J.P. Morgan	Global Banks	13,522
78	Honda	Cars	13,332
79	Pepsi	Soft Drinks	13,134
80	Ford	Cars	13,106
81	BP	Oil & Gas	12,938
82	Telstra	Telecom Providers	12,701
83	KFC	Fast Food	12,649
84	Westpac	Regional Banks	12,420
85	Linkedin	Technology	12,200
86	Santander	Global Banks	12,181
87	Woolworths	Retail	11,818
88	PayPal	Payments	11,806
89	Chase	Regional Banks	11,661
90	Aldi	Retail	11,660
91	ING	Global Banks	11,560
92	Twitter	Technology	11,447
93	Nissan	Cars	11,411
94	Red Bull	Soft Drinks	11,375
95	Bank of America	Regional Banks	11,335
96	NTT DOCOMO	Telecom Providers	11,223
97	Costco Wholesale	Retail	11,214
98	Soft Bank	Telecom Providers	11,131
99	China Telecom	Telecom Providers	11,075
100	Scotiabank	Regional Banks	11,044

Interbrand | Best Global Brands 2015 | Top 100

Rank	Brand	Sector	Brand Value (M)
1	Apple	Technology	170,276
2	Google	Technology	120,314
3	Coca-Cola	Soft Drinks	78,423
4	Microsoft	Technology	67,670
5	IBM	Technology	65,095
6	Toyota	Cars	49,048
7	Samsung	Technology	45,297
8	General Electric	Conglomerate	42,267
9	McDonald's	Fast Food	39,809
10	Amazon.com	Retail	37,948
11	BMW	Cars	37,212
12	Mercedes-Benz	Cars	36,711
13	Disney	Entertainment	36,514
14	Intel	Technology	35,415
15	Cisco	Technology	29,854
16	Oracle	Technology	27,283
17	Nike	Apparel	23,070
18	HP	Technology	23,056
19	Honda	Cars	22,975
20	Louis Vuitton	Luxury	22,250
21	H&M	Apparel	22,222
22	Gillette	Personal Care	22,218
23	Facebook	Technology	22,029
24	Pepsi	Soft Drinks	19,622
25	American Express	Payments	18,922
26	SAP	Technology	18,768
27	IKEA	Retail	16,541
28	Pampers	Baby Care	15,267
29	UPS	Logistics	14,723
30	ZARA	Apparel	14,031
31	Budweiser	Beer	13,943
32	eBay	Retail	13,940
33	J.P. Morgan	Global Banks	13,749
34	Kelloggs	FMCG	12,637
35	Volkswagen	Cars	12,545
36	Nescafé	Beverages	12,257
37	HSBC	Global Banks	11,656
38	Ford	Cars	11,578
39	Hyundai	Cars	11,293
40	Canon	Electronics	11,278
41	Hermes Paris	Luxury	10,944
42	Accenture	Technology	10,800
43	L'Oréal Paris	Personal Care	10,798
44	Audi	Cars	10,328
45	Citi	Global Banks	9,784
46	Goldman Sachs	Financial Services	9,526
47	Philips	Electronics	9,400
48	AXA	Financial Services	9,254
49	Nissan	Cars	9,082
50	Gucci	Luxury	8,882
51	Danone	FMCG	8,632
52	Nestlé	FMCG	8,588
53	Siemens	Technology	8,553
54	Allianz	Financial Services	8,498
55	Colgate	Personal Care	8,464
56	Porsche	Cars	8,055
57	Cartier	Luxury	7,924
58	Sony	Electronics	7,702
59	3M	Diversified	7,243
60	Morgan Stanley	Financial Services	7,083
61	Visa	Payments	6,870
62	Adidas	Sporting Goods	6,811
63	Thomson Reuters	Media	6,583
64	Discovery Channel	Media	6,509
65	Panasonic	Electronics	6,436
66	Tiffany & Co	Luxury	6,306
67	Starbucks	Restaurants	6,266
68	Adobe	Technology	6,257
69	Prada	Luxury	6,222
70	Santander	Restaurants	6,097
71	Xerox	Business Services	6,033
72	Caterpillar	Diversified	5,976
73	Burberry	Luxury	5,873
74	KIA Motors	Cars	5,666
75	Kentucky Fried Chicken	Fast Food	5,639
76	MasterCard	Payments	5,551
77	Johnson and Johnson	FMCG	5,533
78	Shell	Oil & Gas	5,530
79	Harley-Davidson	Automotive	5,460
80	DHL	Logistics	5,391
81	Sprite	Beverages	5,365
82	Lego	FMCG	5,362
83	Deere & Company	Diversified	5,208
84	Jack Daniels	Alcohol	5,161
85	Chevrolet	Cars	5,133
86	FedEx	Logistics	5,130
87	Land Rover	Cars	5,109
88	Huawei	Technology	4,952
89	Heineken	Alcohol	4,822
90	MTV	Media	4,763
91	Ralph Lauren	Apparel	4,629
92	Johnnie Walker	Alcohol	4,540
93	Corona	Alcohol	4,456
94	Smirnoff	Alcohol	4,407
95	Kleenex	FMCG	4,330
96	Hugo Boss	Apparel]	4,270
97	PayPal	Payments	4,251
98	MINI	Cars	4,243
99	Moët et Chandon	Alcohol	4,131
100	Lenovo	Technology	4,114